PROTACs-induced targeted health proteins deterioration has surfaced being a innovative restorative technique in medicine advancement and attracted the favor of academic establishments, sizeable pharmaceutic businesses (e.g., AstraZeneca, Bayer, Novartis, Amgen, Pfizer, GlaxoSmithKline, Merck, and Boehringer Ingelheim, and so on.), and biotechnology organizations. PROTACs opened a new chapter for unique medicine development. Views about the prospective prospects and problems of PROTACs will contribute to the study and progression of new proteins degradation prescription drugs and degrader tools.
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•Degrade the “undruggable” health proteins target；
•Quick and reversible chemical substance knockdown method in vivo.
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