(+)-JQ1 is actually a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cellular-free assays, binding to any or all bromodomains of your Option family members, although not to bromodomains beyond the Option family members.
Connected Merchandise: GSK6853, CPI-637
CHIR-99021 (CT99021) can be a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, correspondingly.
Associated Goods: TDZD-8 , SB 216763
PD98059 is actually a non-ATP very competitive MEK inhibitor with IC50 of 2 μM inside a mobile-free of charge assay, specifically inhibits MEK-1-mediated activation of MAPK fails to directly slow down ERK1 or ERK2.
Related Goods: GDC-0623 , APS-2-79
Forskolin can be a all-pervasive activator of eukaryotic adenylyl cyclase (AC) in a multitude of mobile types, commonly used to raise degrees of camp out from the review and research of cellular physiology.
Related Items: Isoprenaline hydrochloride
Potent and picky G9a/GLP histone lysine methyltransferase inhibitor (IC50= 3.3 nM).
Associated Merchandise: DIM-C-pPhOH , CCT241736
45 forms of substance libraries for top throughput screening and high articles testing.
DNA Injury/DNA Restoration
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