Homology-reliant DNA Restoration Inhibitor
YU238259 is really a novel inhibitor of homology-dependent DNA repair(HDR), but is not going to slow down non-homologous end-enrolling in (NHEJ), in mobile-based GFP reporter assays.
Associated Goods:Bucladesine salt salt
PF-04929113 Mesylate, a prodrug of SNX-2112, is surely an orally productive Hsp90 inhibitor, by using a Kd of 41 nM, plus induces Her-2 degradation, with the IC50 of 37 nM.
Connected Products: Resminostat hydrochloridel
Histone methyltransferase Inhibitor
A-196 is really a effective and picky inhibitor of SUV420H1 and SUV420H2 with IC50 principles of .025 and .144 μM, correspondingly greater than 100-fold selective over other histone methyltransferases and non-epigenetic focuses on..
Relevant Products: Air conditioning-CoA Synthase Inhibitor1
Ephrin Receptor inhibitor
ALW-II-41-27 is actually a novel Eph receptor tyrosine kinase inhibitor, useful for malignancy remedy.
Related Merchandise: Pimodivir , MS049
Tyrosine Kinases inhibitor
Sitravatinib (MGCD516) is actually a novel modest molecule inhibitor targeting several RTKs associated with driving a vehicle sarcoma cell development, such as c-Package, PDGFRβ, PDGFRα, c-Satisfied, and Axl.
Related Items: Miriplatin ,RAD140
45 varieties of substance libraries for high throughput testing and content material evaluating.
DNA Problems/DNA Repair
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