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Popular Materials in Apoptosis Chemical substance Group catalogue

Procaspase-3

PAC-1 CAS No. 315183-21-2

PAC-1 might be a reliable procaspase-3 activator with EC50 of .22 μM as well as the original modest molecule seen to directly initialize procaspase-3 to caspase-3.

p53

Pifithrin-α CAS No. 63208-82-2

Pifithrin-α is definitely an inhibitor of p53, suppressing p53-structured transactivation of p53-susceptible genes.

Bcl-2 MCL-1

A-1210477 CAS No. 1668553-26-1

A-1210477 is truly a potent and particular MCL-1 and Bcl-2 inhibitor with Ki and IC50 of .454 nM and 26.2 nM, respectively,Andgt100-slip selectivity over other Bcl-2 people in your family.

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