Procaspase-3
PAC-1 CAS No. 315183-21-2
PAC-1 might be a reliable procaspase-3 activator with EC50 of .22 μM as well as the original modest molecule seen to directly initialize procaspase-3 to caspase-3.
p53
Pifithrin-α CAS No. 63208-82-2
Pifithrin-α is definitely an inhibitor of p53, suppressing p53-structured transactivation of p53-susceptible genes.
Bcl-2 MCL-1
A-1210477 CAS No. 1668553-26-1
A-1210477 is truly a potent and particular MCL-1 and Bcl-2 inhibitor with Ki and IC50 of .454 nM and 26.2 nM, respectively,Andgt100-slip selectivity over other Bcl-2 people in your family.
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