VX-11e Chemical substance CompositionNLG919Discover More>>
NLG919 can be a effective IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cellular-cost-free assays. Stage 1.
Relevant Merchandise: Indoximod, INCB024360 analogue
Trovirdine (LY-300046) Compound ConstructionCPI-1189Get More Information>>
CPI-1189(REN-1189) is really a TNF-α discharge inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
Connected Goods: CX691 , Substance 4
DB07268 Compound StructureValrocemideLearn More>>
Valrocemide(Tv set-1901), is surely an antiepileptic medication (AED). Valrocemide carries a large spectrum of anticonvulsant activity and promising probable like a new AED.
Relevant Merchandise: Lvguidingan , NS 638
BML-210 Compound StructureSU 5205Get More Information>>
SU 5205 is actually a VEGFR2 inhibitor.
Associated Goods: PF-CBP1 , SR-3029
AMG-337 Substance CompositionNSC 86429Find Out More>>
SU-4312, also known as DMBI, is really a potent and picky inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 principles are .8 and 19.4 μM respectively). SU4312 unexpectedly guards against MPP(+) -induced neurotoxicity via particular and primary inhibition of neuronal NOS.
Relevant Merchandise: I-CBP112 , GK921
IKr Station Blocker
JNJ-42165279 Substance CompositionCK-1752Discover More>>
Sematilide, also called CK-1752, is really a course III antiarrhythmic. It is a selective slowed rectifier K+ present (IKr) route blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, causing the prolongation of action probable period and refractoriness.
Connected Products: XL-652 , WAY 200070