Popular Production

ALK inhibitor

Brigatinib Substance StructureBrigatinib

Brigatinib can be a highly potent and picky investigational ALK inhibitor with mean IC50 value < 100 nM in Ba/F3 tissue.

Reference Generation: LDN193189, LDK378(Ceritinib)

JAK inhibitor

Solcitinib Substance CompositionSolcitinib

Solcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibitor. Solcitinib may be possible a good choice for treatments for psoriasis,systemic lupus erythematosus, ulcerative colitis.

Reference point Production: TG101209 , TAK901

Opioid Receptor Inhibitor

Protopine Chemical substance FrameworkProtopine

Protopine can be a benzylisoquinoline alkaloid. It has been identified to hinder histamine H1 receptors and platelet aggregation, and works for an analgesic.

Reference point Manufacturing: Eluxadoline , JTC-801

SHP2 Inhibitor

SHP099 hydrochloride Chemical substance ConstructionSHP099 hydrochloride

SHP099 hydrochloride is a picky and orally bioavailable little-molecule SHP2 inhibitor with IC50 of .071 μM.

Guide Production: Molsidomine

PARP Inhibitor

VerbascosideSubstance CompositionVerbascoside

Verbascoside (Acteoside TJC160), can be a bioactive polyphenol from essential olive oil mill wastewater with acknowledged antioxidant action proteins kinase C inhibitor.

Research Creation: JNJ-42041935 , Daprodustat

EGFR Inhibitor

Anlotinib  Substance FrameworkAnlotinib

Anlotinib  can be a EGFR inhibitor extracted from patent 2015185012 A1, compound 1,which enables you to handle non-modest cell cancer of the lung.

Research Production: OSI-420 , Varlitinib




JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling





DNA Injury/DNA Maintenance

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