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Preferred Generation in Epigenetics Ingredient Catalogue

Histone Methyltransferase

EPZ004777 CAS No. 1338466-77-5

EPZ004777 can be a strong, discerning DOT1L inhibitor with IC50 of .4 nM in a mobile phone-free assay.

Epigenetic Viewer Domain name

I-BET151 CAS No. 1300031-49-5

I-BET151 (GSK1210151A) can be a novel discerning Wager inhibitor for BRD2, BRD3 and BRD4 with IC50 of .5 μM, .25 μM, and .79 μM in cell-totally free assays, correspondingly.

DNA Methyltransferase

SGI-1027  CAS No. 1020149-73-8

SGI-1027  can be a strong and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, correspondingly.

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