Modest Substances, Huge Roles

Cyclopamine Chemical substance ConstructionCyclopamine

Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 tissue.

Research emphasize: Contact with cyclopamine promotes pancreatic development in embryonic girls. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)

This product is available in : Bioactive Ingredient Library, Organic Compound Library

TWS119 Compound StructureTWS119

TWS119 is actually a GSK-3β inhibitor with IC50 of 30 nM inside a mobile phone-free of charge assay competent at inducing neuronal differentiation and might be of use to originate mobile phone biology.

Analysis emphasize: TWS119, a 4,6-disubstituted pyrrolopyrimidine that may stimulate neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003,100(13): 7632-7637. )

This device features in : Bioactive Substance Library

Nicotinamide Compound CompositionNicotinamide

Nicotinamide (Nutritional B3), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, plus serve as an activator of sirtuins.

Analysis emphasize: nicotinamide improved the deliver of differentiation of Embryonic Come Tissue to pancreatic endocrine tissue (Lumelsky N,et,al.Science, 2001, 292(5520): 1389-1394 )

This product includes in : Approved Drug Library, Organic Compound Local library

Testing libraries to recognize much more functionally special tiny molecules!

Contains 3071 small molecule materials

An original variety of 1700 approved medicines

Contains 640 all-natural substances

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