Cyclopamine Chemical substance ConstructionCyclopamine
Cyclopamine is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 tissue.
Research emphasize: Contact with cyclopamine promotes pancreatic development in embryonic girls. (Kim SK, et,al. PNAS, 1998, 95: 13036-13041.)
This product is available in : Bioactive Ingredient Library, Organic Compound Library
TWS119 Compound StructureTWS119
TWS119 is actually a GSK-3β inhibitor with IC50 of 30 nM inside a mobile phone-free of charge assay competent at inducing neuronal differentiation and might be of use to originate mobile phone biology.
Analysis emphasize: TWS119, a 4,6-disubstituted pyrrolopyrimidine that may stimulate neurogenesis in murine ESCs. (Ding S, et,al. PNAS, 2003，100(13): 7632-7637. )
This device features in : Bioactive Substance Library
Nicotinamide Compound CompositionNicotinamide
Nicotinamide (Nutritional B3), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, plus serve as an activator of sirtuins.
Analysis emphasize: nicotinamide improved the deliver of differentiation of Embryonic Come Tissue to pancreatic endocrine tissue (Lumelsky N,et,al.Science, 2001, 292(5520): 1389-1394 )
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