Rock and roll and roll inhibitor
Y-27632 dihydrochloride is truly a specific ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, uncovers>200-fold selectivity over other kinases, that come with PKC, camp out out-centered healthful protein kinase, MLCK and PAK.
Relevant Products: Thiazovivin, Fasudil (HA-1077) HCl
CHIR-99021 (CT99021) HCl is hydrochloride of CHIR-99021, and that is certainly certainly a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM capacity to specific GSK-3 as well as its nearest homologs Cdc2 and ERK2.
Linked Products: SB216763 , CHIR-98014
MG-132 is unquestionably an inhibitor of proteasome with IC50 of 100 nM, and likewise inhibits calpain with IC50 of 1.2 μM.
Connected Goods: Carfilzomib (PR-171) , ONX-0914 (PR-957)
Romidepsin (FK228, Depsipeptide)
Romidepsin (FK228, depsipeptide) could be a highly effective HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, correspondingly.
Affixed Goods: Entinostat (MS-275) , Trichostatin A (TSA)
MK-2206 2HCl is actually a highly a number of inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, correspondingly no inhibitory actions against 250 other protein kinases noticed. Cycle 2.
Associated Merchandise: AZD5363 , GDC-0068
Vemurafenib (PLX4032, RG7204) is truly a particular and powerful inhibitor of B-RafV600E with IC50 of 31 nM.
Important Goods: Sorafenib Tosylate , PLX-4720
Goods and services Catalog
32 varieties of aspect libraries for major throughput analyzing and information confirmation.
DNA Cause damage to/DNA Restoration
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