proteasome
CAS No. 133407-82-6
MG-132 is definitely an inhibitor of proteasome with IC50 of 100 nM inside a cellular-cost-free assay, plus inhibits calpain with IC50 of 1.2 μM.
CAS No. 179324-69-7
Bortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of .6 nM within a cell-totally free assay.
CAS No. 868540-17-4
Carfilzomib (PR-171) is undoubtedly an irrevocable proteasome inhibitor with IC50 of 5 nM in ANBL-6 tissue, exhibited preferential in vitro inhibitory power versus the ChT-L exercise in the β5 subunit, but a minimum of impact on the PGPH and T-L pursuits.
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