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Warm Substances in Protease Inhibitor Library

proteasome

MG-132

CAS No. 133407-82-6

MG-132 is definitely an inhibitor of proteasome with IC50 of 100 nM inside a cellular-cost-free assay, plus inhibits calpain with IC50 of 1.2 μM.

Bortezomib

CAS No. 179324-69-7

Bortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of .6 nM within a cell-totally free assay.

Carfilzomib

CAS No. 868540-17-4

Carfilzomib (PR-171) is undoubtedly an irrevocable proteasome inhibitor with IC50 of 5 nM in ANBL-6 tissue, exhibited preferential in vitro inhibitory power versus the ChT-L exercise in the β5 subunit, but a minimum of impact on the PGPH and T-L pursuits.

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